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Stereoconvergent Negishi Arylations of Racemic Secondary Alkyl Electrophiles: Differentiating Between a CF(3) and an Alkyl Group

In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a wide array of enantioconvergent cross-couplings of arylzinc reagents with CF(3)-substituted racemic secondary alkyl halides, a process that necessitates that the chiral catalyst be able to effectively...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Liang, Yufan, Fu, Gregory C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610818/
https://ncbi.nlm.nih.gov/pubmed/26203662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04725
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