Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer

PURPOSE: The failure of colorectal cancer treatments is partly due to overexpression of CXCR4 by tumor cells, which plays a critical role in cell metastasis. Moreover, serum alkaline phosphatase (ALP) levels are frequently elevated in patients with metastatic colorectal cancer. A polysaccharide, dex...

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Detalhes bibliográficos
Main Authors: Abedini, Fatemeh, Hosseinkhani, Hossein, Ismail, Maznah, Domb, Abraham J, Omar, Abdul Rahman, Chong, Pei Pei, Hong, Po-Da, Yu, Dah-Shyong, Farber, Ira-Yudovin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415322/
https://ncbi.nlm.nih.gov/pubmed/22888250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29823
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