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Intranasal Brain Delivery of Cationic Nanoemulsion-Encapsulated TNFα siRNA in Prevention of Experimental Neuroinflammation

Neuroinflammation is a hallmark of acute and chronic neurodegenerative disorders. Activated microglia and secreted factors such as tumor necrosis factor-alpha (TNFα) are key mediators of neuroinflammation and may contribute to neuronal dysfunction. The main aim of this study was to evaluate the ther...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nanomedicine
Main Authors: Yadav, Sunita, Gandham, Srujan K., Panicucci, Riccardo, Amiji, Mansoor M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837036/
https://ncbi.nlm.nih.gov/pubmed/26767514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.12.374
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