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CNS Delivery and Anti-Inflammatory Effects of Intranasally Administered Cyclosporine-A in Cationic Nanoformulations

The main objective of this study was to develop and evaluate the CNS delivery efficiency, distribution, therapeutic efficacy, and safety of cyclosporine A (CSA) using a cationic oil-in-water nanoemulsion system upon intranasal administration. An omega-3 fatty acid–rich, flaxseed oil–based nanoemulsi...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Yadav, Sunita, Pawar, Grishma, Kulkarni, Praveen, Ferris, Craig, Amiji, Mansoor
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806630/
https://ncbi.nlm.nih.gov/pubmed/30591529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.254672
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