Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver

Liver metastasis is the main cause of mortality related to colorectal cancer. CXCR4 is necessary for the outgrowth of colon cancer micrometastases. In oncology, it has been demonstrated that several human tumors release lactate dehydrogenase (LDH) into the circulation. CXCR4 gene expression and seru...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Abedini, Fatemeh, Ismail, Maznah, Hosseinkhani, Hossein, Ibrahim, Tengku Azmi Tengku, Omar, Abdul Rahman, Chong, Pei Pei, Bejo, Mohd Hair, Domb, Abraham J
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2011
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173020/
https://ncbi.nlm.nih.gov/pubmed/21931504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMR.S11678
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