Gene Transfer into the Lung by Nanoparticle Dextran-Spermine/Plasmid DNA Complexes

A novel cationic polymer, dextran-spermine (D-SPM), has been found to mediate gene expression in a wide variety of cell lines and in vivo through systemic delivery. Here, we extended the observations by determining the optimal conditions for gene expression of D-SPM/plasmid DNA (D-SPM/pDNA) in cell...

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Detalhes bibliográficos
Main Authors: Abdullah, Syahril, Wendy-Yeo, Wai Yeng, Hosseinkhani, Hossein, Hosseinkhani, Mohsen, Masrawa, Ehab, Ramasamy, Rajesh, Rosli, Rozita, Rahman, Sabariah A., Domb, Abraham J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896664/
https://ncbi.nlm.nih.gov/pubmed/20617146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/284840
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