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How do alignment programs perform on sequencing data with varying qualities and from repetitive regions?
BACKGROUND: Next-generation sequencing technologies generate a significant number of short reads that are utilized to address a variety of biological questions. However, quite often, sequencing reads tend to have low quality at the 3’ end and are generated from the repetitive regions of a genome. It...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414812/ https://ncbi.nlm.nih.gov/pubmed/22709551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-5-6 |
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