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MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer

Conflicting reports exist regarding the contribution of SNP309 in MDM2 to cancer risk. Recently, SNP285 was shown to act as an antagonist to SNP309 by over-riding the effect of SNP309 on SP1-mediated transcription. Moreover, SNP285 modified the relationship between SNP309 and risk of breast, ovarian...

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Autori principali: Ryan, Bríd M., Calhoun, Kara M., Pine, Sharon R., Bowman, Elise D., Robles, Ana I., Ambs, Stefan, Harris, Curtis C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414691/
https://ncbi.nlm.nih.gov/pubmed/22487911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27573
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