Constitutive Cleavage of the Single-Pass Transmembrane Protein Alcadeinα Prevents Aberrant Peripheral Retention of Kinesin-1

Eitemau Tebyg

• Mechanism of Intramembrane Cleavage of Alcadeins by γ-Secretase
  gan: Piao, Yi, et al.
  Cyhoeddwyd: (2013)
• Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α–deficient mice
  gan: Gotoh, Naoya, et al.
  Cyhoeddwyd: (2020)
• Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo
  gan: Sobu, Yuriko, et al.
  Cyhoeddwyd: (2017)
• The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport
  gan: Araki, Yoichi, et al.
  Cyhoeddwyd: (2007)
• Cytoplasmic Fragment of Alcadein α Generated by Regulated Intramembrane Proteolysis Enhances Amyloid β-Protein Precursor (APP) Transport into the Late Secretory Pathway and Facilitates APP Cleavage
  gan: Takei, Norio, et al.
  Cyhoeddwyd: (2015)