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Anergy Induction by Dimeric TCR Ligands()

T cells that recognize particular self Ags are thought to be important in the pathogenesis of autoimmune diseases. In multiple sclerosis, susceptibility is associated with HLA-DR2, which can present myelin-derived peptides to CD4(+) T cells. To generate molecules that target such T cells based on th...

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Bibliographic Details
Main Authors: Appel, Heiner, Seth, Nilufer P., Gauthier, Laurent, Wucherpfennig, Kai W.
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414419/
https://ncbi.nlm.nih.gov/pubmed/11290814
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