Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy

Mocholi et al. show that, following T cell activation, activation of autophagy constitutes a tolerance-avoidance mechanism that, through modulation of cell metabolism and specific signaling pathways, allows T cells to engage in effector responses and avoid anergy. In vivo inhibition of autophagy in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Mocholi, Enric, Dowling, Samuel D., Botbol, Yair, Gruber, Ross C., Ray, Alex K., Vastert, Sebastiaan, Bridget, Shafit-Zagardo, Coffer, Paul J., Macian, Fernando
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109966/
https://ncbi.nlm.nih.gov/pubmed/30067971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.065
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk