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Quantitative Model of Cell Cycle Arrest and Cellular Senescence in Primary Human Fibroblasts
Primary human fibroblasts in tissue culture undergo a limited number of cell divisions before entering a non-replicative “senescent” state. At early population doublings (PD), fibroblasts are proliferation-competent displaying exponential growth. During further cell passaging, an increasing number o...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413708/ https://ncbi.nlm.nih.gov/pubmed/22879912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042150 |
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