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Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development

Mutations in the human Shwachman-Bodian-Diamond syndrome (SBDS) gene cause defective ribosome assembly and are associated with exocrine pancreatic insufficiency, chronic neutropenia and skeletal defects. However, the mechanism underlying these phenotypes remains unclear. Here we show that knockdown...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Provost, Elayne, Wehner, Karen A., Zhong, Xiangang, Ashar, Foram, Nguyen, Elizabeth, Green, Rachel, Parsons, Michael J., Leach, Steven D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Company of Biologists 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413166/
https://ncbi.nlm.nih.gov/pubmed/22872088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077107
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