Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development

Mutations in the human Shwachman-Bodian-Diamond syndrome (SBDS) gene cause defective ribosome assembly and are associated with exocrine pancreatic insufficiency, chronic neutropenia and skeletal defects. However, the mechanism underlying these phenotypes remains unclear. Here we show that knockdown...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Provost, Elayne, Wehner, Karen A., Zhong, Xiangang, Ashar, Foram, Nguyen, Elizabeth, Green, Rachel, Parsons, Michael J., Leach, Steven D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2012
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413166/
https://ncbi.nlm.nih.gov/pubmed/22872088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077107
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