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Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development
Mutations in the human Shwachman-Bodian-Diamond syndrome (SBDS) gene cause defective ribosome assembly and are associated with exocrine pancreatic insufficiency, chronic neutropenia and skeletal defects. However, the mechanism underlying these phenotypes remains unclear. Here we show that knockdown...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413166/ https://ncbi.nlm.nih.gov/pubmed/22872088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077107 |
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