Anterior-posterior differences in HoxD chromatin topology in limb development

A late phase of HoxD activation is crucial for the patterning and growth of distal structures across the anterior-posterior (A-P) limb axis of mammals. Polycomb complexes and chromatin compaction have been shown to regulate Hox loci along the main body axis in embryonic development, but the extent t...

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Main Authors: Williamson, Iain, Eskeland, Ragnhild, Lettice, Laura A., Hill, Alison E., Boyle, Shelagh, Grimes, Graeme R., Hill, Robert E., Bickmore, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2012
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413162/
https://ncbi.nlm.nih.gov/pubmed/22872084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.081174
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