DNA Ends Alter the Molecular Composition and Localization of Ku Multicomponent Complexes

The Ku heterodimer plays an essential role in non-homologous end-joining and other cellular processes including transcription, telomere maintenance and apoptosis. While the function of Ku is regulated through its association with other proteins and nucleic acids, the specific composition of these ma...

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Hauptverfasser: Adelmant, Guillaume, Calkins, Anne S., Garg, Brijesh K., Card, Joseph D., Askenazi, Manor, Miron, Alex, Sobhian, Bijan, Zhang, Yi, Nakatani, Yoshihiro, Silver, Pamela A., Iglehart, J. Dirk, Marto, Jarrod A., Lazaro, Jean-Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412971/
https://ncbi.nlm.nih.gov/pubmed/22535209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013581
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