Online Nanoflow RP-RP-MS Reveals Dynamics of Multi-component Ku Complex in Response to DNA Damage

Tandem affinity purification (TAP) coupled with mass spectrometry has become the technique of choice for characterization of multi-component protein complexes. While current TAP protocols routinely provide high yield and specificity for proteins expressed under physiologically relevant conditions, a...

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Main Authors: Zhou, Feng, Cardoza, Job D., Ficarro, Scott B., Adelmant, Guillaume O., Lazaro, Jean-Bernard, Marto, Jarrod A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997187/
https://ncbi.nlm.nih.gov/pubmed/20873769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1004696
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