High-Throughput Screening and Rapid Inhibitor Triage Using an Infectious Chimeric Hepatitis C Virus

The recent development of a Hepatitis C virus (HCV) infectious virus cell culture model system has facilitated the development of whole-virus screening assays which can be used to interrogate the entire virus life cycle. Here, we describe the development of an HCV growth assay capable of identifying...

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Detalhes bibliográficos
Main Authors: Wichroski, Michael J., Fang, Jie, Eggers, Betsy J., Rose, Ronald E., Mazzucco, Charles E., Pokornowski, Kevin A., Baldick, Carl J., Anthony, Monique N., Dowling, Craig J., Barber, Lauren E., Leet, John E., Beno, Brett R., Gerritz, Samuel W., Agler, Michele L., Cockett, Mark I., Tenney, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412796/
https://ncbi.nlm.nih.gov/pubmed/22880053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042609
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