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A Novel Small Molecule Inhibitor of Hepatitis C Virus Entry

Small molecule inhibitors of hepatitis C virus (HCV) are being developed to complement or replace treatments with pegylated interferons and ribavirin, which have poor response rates and significant side effects. Resistance to these inhibitors emerges rapidly in the clinic, suggesting that successful...

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Autors principals: Baldick, Carl J., Wichroski, Michael J., Pendri, Annapurna, Walsh, Ann W., Fang, Jie, Mazzucco, Charles E., Pokornowski, Kevin A., Rose, Ronald E., Eggers, Betsy J., Hsu, Mayla, Zhai, Weixu, Zhai, Guangzhi, Gerritz, Samuel W., Poss, Michael A., Meanwell, Nicholas A., Cockett, Mark I., Tenney, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936744/
https://ncbi.nlm.nih.gov/pubmed/20838466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001086
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