A Novel Small Molecule Inhibitor of Hepatitis C Virus Entry

Small molecule inhibitors of hepatitis C virus (HCV) are being developed to complement or replace treatments with pegylated interferons and ribavirin, which have poor response rates and significant side effects. Resistance to these inhibitors emerges rapidly in the clinic, suggesting that successful...

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Main Authors: Baldick, Carl J., Wichroski, Michael J., Pendri, Annapurna, Walsh, Ann W., Fang, Jie, Mazzucco, Charles E., Pokornowski, Kevin A., Rose, Ronald E., Eggers, Betsy J., Hsu, Mayla, Zhai, Weixu, Zhai, Guangzhi, Gerritz, Samuel W., Poss, Michael A., Meanwell, Nicholas A., Cockett, Mark I., Tenney, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936744/
https://ncbi.nlm.nih.gov/pubmed/20838466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001086
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