Ultrasensitive Genotypic Detection of Antiviral Resistance in Hepatitis B Virus Clinical Isolates

Amino acid substitutions that confer reduced susceptibility to antivirals arise spontaneously through error-prone viral polymerases and are selected as a result of antiviral therapy. Resistance substitutions first emerge in a fraction of the circulating virus population, below the limit of detection...

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Detaylı Bibliyografya
Asıl Yazarlar: Fang, Jie, Wichroski, Michael J., Levine, Steven M., Baldick, Carl J., Mazzucco, Charles E., Walsh, Ann W., Kienzle, Bernadette K., Rose, Ronald E., Pokornowski, Kevin A., Colonno, Richard J., Tenney, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704686/
https://ncbi.nlm.nih.gov/pubmed/19433559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00130-09
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