Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization

The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, is a common inhabitant of the human upper aerodigestive tract. The organism produces an RTX (Repeats in ToXin) toxin (LtxA) that kills human white blood cells. LtxA is believed to be a membrane-damaging toxin, but details of the cel...

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Detaylı Bibliyografya
Asıl Yazarlar: Brown, Angela C., Boesze-Battaglia, Kathleen, Du, Yurong, Stefano, Frank P., Kieba, Irene R., Epand, Raquel F., Kakalis, Lazaros, Yeagle, Philip L., Epand, Richard M., Lally, Edward T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412409/
https://ncbi.nlm.nih.gov/pubmed/22309134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01762.x
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