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Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, is a common inhabitant of the human upper aerodigestive tract. The organism produces an RTX (Repeats in ToXin) toxin (LtxA) that kills human white blood cells. LtxA is believed to be a membrane-damaging toxin, but details of the cel...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412409/ https://ncbi.nlm.nih.gov/pubmed/22309134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01762.x |
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