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Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

Lysosomes are responsible for degradation and recycling of bulky cell material, including accumulated misfolded proteins and dysfunctional organelles. Increasing evidence implicates lysosomal dysfunction in several neurodegenerative disorders, including Parkinson's disease and related synuclein...

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Hlavní autoři: Usenovic, Marija, Knight, Adam L., Ray, Arpita, Wong, Victoria, Brown, Kevin R., Caldwell, Guy A., Caldwell, Kim A., Stagljar, Igor, Krainc, Dimitri
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412378/
https://ncbi.nlm.nih.gov/pubmed/22645275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds206
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