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Initial steps in the opening of a Shaker potassium channel

The structural model of a K(V) (K(+)-selective, voltage-gated) channel in the open state is known (Protein Data Bank ID code 2R9R). Each subunit of the channel has four negatively charged residues distributed in the transmembrane segments S1, S2, and S3 that bind to and facilitate the movement withi...

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Detalles Bibliográficos
Main Authors: Hoshi, Toshinori, Armstrong, Clay M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412037/
https://ncbi.nlm.nih.gov/pubmed/22802655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209665109
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