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Initial steps in the opening of a Shaker potassium channel

The structural model of a K(V) (K(+)-selective, voltage-gated) channel in the open state is known (Protein Data Bank ID code 2R9R). Each subunit of the channel has four negatively charged residues distributed in the transmembrane segments S1, S2, and S3 that bind to and facilitate the movement withi...

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Bibliografiske detaljer
Main Authors: Hoshi, Toshinori, Armstrong, Clay M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412037/
https://ncbi.nlm.nih.gov/pubmed/22802655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209665109
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