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Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression

The nervous system maintains a delicate balance between excitation and inhibition, partly through the complex interplay between voltage-gated sodium and potassium ion channels. Because K(+) channel blockade or gene deletion causes hyperexcitability, it is generally assumed that increases in K(+) cha...

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Detalhes bibliográficos
Main Authors: Sutherland, M. L., Williams, S. H., Abedi, R., Overbeek, P. A., Pfaffinger, P. J., Noebels, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26805/
https://ncbi.nlm.nih.gov/pubmed/10051663
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