Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression

The nervous system maintains a delicate balance between excitation and inhibition, partly through the complex interplay between voltage-gated sodium and potassium ion channels. Because K(+) channel blockade or gene deletion causes hyperexcitability, it is generally assumed that increases in K(+) cha...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sutherland, M. L., Williams, S. H., Abedi, R., Overbeek, P. A., Pfaffinger, P. J., Noebels, J. L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2451
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