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miR-29ab1-deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias that is Dysregulated in Multiple Sclerosis()
T-helper cell programming and function is tightly regulated by complex biological networks to prevent excessive inflammatory responses and autoimmune disease. The importance of miRNAs in this process is highlighted by the preferential Th1 polarization of Dicer-deficient T cells that lack miRNAs. Usi...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411895/ https://ncbi.nlm.nih.gov/pubmed/22772450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103171 |
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