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TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion

Transforming growth factor-β (TGFβ) promotes glomerular hypertrophy and matrix expansion, leading to glomerulosclerosis. MicroRNAs are well suited to promote fibrosis because they can repress gene expression, which negatively regulate the fibrotic process. Recent cellular and animal studies have rev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dey, Nirmalya, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411779/
https://ncbi.nlm.nih.gov/pubmed/22879939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042316
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