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Two Deafness-causing (DFNA20/26) Actin Mutations Affect Arp2/3-dependent Actin Regulation
Hearing requires proper function of the auditory hair cell, which is critically dependent upon its actin-based cytoskeletal structure. Currently, ten point mutations in nonmuscle γ-actin have been identified as causing progressive autosomal dominant nonsyndromic hearing loss (DFNA20/26), highlightin...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411063/ https://ncbi.nlm.nih.gov/pubmed/22718764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377283 |
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