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Allele-specific Effects of Human Deafness γ-Actin Mutations (DFNA20/26) on the Actin/Cofilin Interaction
Auditory hair cell function requires proper assembly and regulation of the nonmuscle gamma isoactin-rich cytoskeleton, and six point mutations in this isoactin cause a type of delayed onset autosomal dominant nonsyndromic progressive hearing loss, DFNA20/26. The molecular basis underlying this actin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709362/ https://ncbi.nlm.nih.gov/pubmed/19419963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.015818 |
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