Azemiopsin from Azemiops feae Viper Venom, a Novel Polypeptide Ligand of Nicotinic Acetylcholine Receptor

Azemiopsin, a novel polypeptide, was isolated from the Azemiops feae viper venom by combination of gel filtration and reverse-phase HPLC. Its amino acid sequence (DNWWPKPPHQGPRPPRPRPKP) was determined by means of Edman degradation and mass spectrometry. It consists of 21 residues and, unlike similar...

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Hauptverfasser: Utkin, Yuri N., Weise, Christoph, Kasheverov, Igor E., Andreeva, Tatyana V., Kryukova, Elena V., Zhmak, Maxim N., Starkov, Vladislav G., Hoang, Ngoc Anh, Bertrand, Daniel, Ramerstorfer, Joachim, Sieghart, Werner, Thompson, Andrew J., Lummis, Sarah C. R., Tsetlin, Victor I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411050/
https://ncbi.nlm.nih.gov/pubmed/22613724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363051
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