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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

The coronaviruses (CoVs) are enveloped viruses of animals and humans associated mostly with enteric and respiratory diseases, such as the severe acute respiratory syndrome and 10–20% of all common colds. A subset of CoVs uses the cell surface aminopeptidase N (APN), a membrane-bound metalloprotease,...

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Autors principals: Reguera, Juan, Santiago, César, Mudgal, Gaurav, Ordoño, Desiderio, Enjuanes, Luis, Casasnovas, José M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410853/
https://ncbi.nlm.nih.gov/pubmed/22876187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002859
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