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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

The coronaviruses (CoVs) are enveloped viruses of animals and humans associated mostly with enteric and respiratory diseases, such as the severe acute respiratory syndrome and 10–20% of all common colds. A subset of CoVs uses the cell surface aminopeptidase N (APN), a membrane-bound metalloprotease,...

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Bibliographische Detailangaben
Hauptverfasser: Reguera, Juan, Santiago, César, Mudgal, Gaurav, Ordoño, Desiderio, Enjuanes, Luis, Casasnovas, José M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410853/
https://ncbi.nlm.nih.gov/pubmed/22876187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002859
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