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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

The coronaviruses (CoVs) are enveloped viruses of animals and humans associated mostly with enteric and respiratory diseases, such as the severe acute respiratory syndrome and 10–20% of all common colds. A subset of CoVs uses the cell surface aminopeptidase N (APN), a membrane-bound metalloprotease,...

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Detalhes bibliográficos
Main Authors: Reguera, Juan, Santiago, César, Mudgal, Gaurav, Ordoño, Desiderio, Enjuanes, Luis, Casasnovas, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410853/
https://ncbi.nlm.nih.gov/pubmed/22876187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002859
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