The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic fun...

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Dettagli Bibliografici
Autori principali: Carty, N C, Xu, J, Kurup, P, Brouillette, J, Goebel-Goody, S M, Austin, D R, Yuan, P, Chen, G, Correa, P R, Haroutunian, V, Pittenger, C, Lombroso, P J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410627/
https://ncbi.nlm.nih.gov/pubmed/22781170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.63
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