The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic fun...

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Detalhes bibliográficos
Main Authors: Carty, N C, Xu, J, Kurup, P, Brouillette, J, Goebel-Goody, S M, Austin, D R, Yuan, P, Chen, G, Correa, P R, Haroutunian, V, Pittenger, C, Lombroso, P J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410627/
https://ncbi.nlm.nih.gov/pubmed/22781170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.63
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