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The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic fun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Carty, N C, Xu, J, Kurup, P, Brouillette, J, Goebel-Goody, S M, Austin, D R, Yuan, P, Chen, G, Correa, P R, Haroutunian, V, Pittenger, C, Lombroso, P J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410627/
https://ncbi.nlm.nih.gov/pubmed/22781170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.63
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