A carregar...
Tankyrase 1 regulates centrosome function by controlling CPAP stability
CPAP—a gene mutated in primary microcephaly—is required for procentriole formation. Here we show that CPAP degradation and function is controlled by the poly(ADP-ribose) polymerase tankyrase 1. CPAP is PARsylated by tankyrase 1 in vitro and in vivo. Overexpression of tankyrase 1 leads to CPAP protea...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410387/ https://ncbi.nlm.nih.gov/pubmed/22699936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.86 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|