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Cell cycle‐regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution

Timely resolution of sister chromatid cohesion in G2/M is essential for genome integrity. Resolution at telomeres requires the poly(ADP‐ribose) polymerase tankyrase 1, but the mechanism that times its action is unknown. Here, we show that tankyrase 1 activity at telomeres is controlled by a ubiquiti...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Tripathi, Ekta, Smith, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694945/
https://ncbi.nlm.nih.gov/pubmed/27993934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695135
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