Membrane protein sequestering by ionic protein-lipid interactions

Neuronal exocytosis is catalyzed by the SNARE protein syntaxin-1A(1). Syntaxin-1A is clustered in the plasma membrane at sites where synaptic vesicles undergo exocytosis(2,3). However, how syntaxin-1A is sequestered is unknown. Here, we show that syntaxin clustering is mediated by electrostatic inte...

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Главные авторы: van den Bogaart, Geert, Meyenberg, Karsten, Risselada, H. Jelger, Amin, Hayder, Willig, Katrin I., Hubrich, Barbara E., Dier, Markus, Hell, Stefan W., Grubmüller, Helmut, Diederichsen, Ulf, Jahn, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409895/
https://ncbi.nlm.nih.gov/pubmed/22020284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10545
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