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The sumLINK statistic for genetic linkage analysis in the presence of heterogeneity
We present the “sumLINK” statistic—the sum of multipoint LOD scores for the subset of pedigrees with nominally significant linkage evidence at a given locus—as an alternative to common methods to identify susceptibility loci in the presence of heterogeneity. We also suggest the “sumLOD” statistic (t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409837/ https://ncbi.nlm.nih.gov/pubmed/19217022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20414 |
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