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Power of Genetic Association Studies in the Presence of Linkage Disequilibrium and Allelic Heterogeneity
OBJECTIVES: The calculation of the power and sample size required for association studies is essential, particularly for follow-up of genome-wide association studies, where much genotyping is required to replicate the original finding and identify the true disease susceptibility mutation. METHODS: I...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787185/ https://ncbi.nlm.nih.gov/pubmed/18612206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000143404 |
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