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Genetic Linkage Analysis in the Presence of Germline Mosaicism

Germline mosaicism is a genetic condition in which some germ cells of an individual contain a mutation. This condition violates the assumptions underlying classic genetic analysis and may lead to failure of such analysis. In this work we extend the statistical model used for genetic linkage analysis...

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Detalhes bibliográficos
Main Authors: Weissbrod, Omer, Geiger, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Berkeley Electronic Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215430/
https://ncbi.nlm.nih.gov/pubmed/23089820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1709
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