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Genetic Linkage Analysis in the Presence of Germline Mosaicism
Germline mosaicism is a genetic condition in which some germ cells of an individual contain a mutation. This condition violates the assumptions underlying classic genetic analysis and may lead to failure of such analysis. In this work we extend the statistical model used for genetic linkage analysis...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Berkeley Electronic Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215430/ https://ncbi.nlm.nih.gov/pubmed/23089820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1709 |
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