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Genetic Linkage Analysis in the Presence of Germline Mosaicism

Germline mosaicism is a genetic condition in which some germ cells of an individual contain a mutation. This condition violates the assumptions underlying classic genetic analysis and may lead to failure of such analysis. In this work we extend the statistical model used for genetic linkage analysis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weissbrod, Omer, Geiger, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Berkeley Electronic Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215430/
https://ncbi.nlm.nih.gov/pubmed/23089820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1709
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