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A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees

Motivation: The use of dense single nucleotide polymorphism (SNP) data in genetic linkage analysis of large pedigrees is impeded by significant technical, methodological and computational challenges. Here we describe Superlink-Online SNP, a new powerful online system that streamlines the linkage ana...

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Detalles Bibliográficos
Main Authors: Silberstein, Mark, Weissbrod, Omer, Otten, Lars, Tzemach, Anna, Anisenia, Andrei, Shtark, Oren, Tuberg, Dvir, Galfrin, Eddie, Gannon, Irena, Shalata, Adel, Borochowitz, Zvi U., Dechter, Rina, Thompson, Elizabeth, Geiger, Dan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546794/
https://ncbi.nlm.nih.gov/pubmed/23162081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts658
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