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Multilocus Lod Scores in Large Pedigrees: Combination of Exact and Approximate Calculations

To detect the positions of disease loci, lod scores are calculated at multiple chromosomal positions given trait and marker data on members of pedigrees. Exact lod score calculations are often impossible when the size of the pedigree and the number of markers are both large. In this case, a Markov C...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tong, Liping, Thompson, Elizabeth
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: S. Karger AG 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701716/
https://ncbi.nlm.nih.gov/pubmed/17934317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000109731
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