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Multilocus Lod Scores in Large Pedigrees: Combination of Exact and Approximate Calculations

To detect the positions of disease loci, lod scores are calculated at multiple chromosomal positions given trait and marker data on members of pedigrees. Exact lod score calculations are often impossible when the size of the pedigree and the number of markers are both large. In this case, a Markov C...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tong, Liping, Thompson, Elizabeth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger AG 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701716/
https://ncbi.nlm.nih.gov/pubmed/17934317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000109731
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