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Multilocus Lod Scores in Large Pedigrees: Combination of Exact and Approximate Calculations

To detect the positions of disease loci, lod scores are calculated at multiple chromosomal positions given trait and marker data on members of pedigrees. Exact lod score calculations are often impossible when the size of the pedigree and the number of markers are both large. In this case, a Markov C...

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Detalhes bibliográficos
Main Authors: Tong, Liping, Thompson, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701716/
https://ncbi.nlm.nih.gov/pubmed/17934317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000109731
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