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Multilocus Lod Scores in Large Pedigrees: Combination of Exact and Approximate Calculations
To detect the positions of disease loci, lod scores are calculated at multiple chromosomal positions given trait and marker data on members of pedigrees. Exact lod score calculations are often impossible when the size of the pedigree and the number of markers are both large. In this case, a Markov C...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
S. Karger AG
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701716/ https://ncbi.nlm.nih.gov/pubmed/17934317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000109731 |
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