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Exact Multipoint Quantitative-Trait Linkage Analysis in Pedigrees by Variance Components

Methods based on variance components are powerful tools for linkage analysis of quantitative traits, because they allow simultaneous consideration of all pedigree members. The central idea is to identify loci making a significant contribution to the population variance of a trait, by use of allele-s...

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Detalhes bibliográficos
Main Authors: Pratt, Stephen C., Daly, Mark J., Kruglyak, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288151/
https://ncbi.nlm.nih.gov/pubmed/10712227
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