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Exact Multipoint Quantitative-Trait Linkage Analysis in Pedigrees by Variance Components

Methods based on variance components are powerful tools for linkage analysis of quantitative traits, because they allow simultaneous consideration of all pedigree members. The central idea is to identify loci making a significant contribution to the population variance of a trait, by use of allele-s...

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Bibliografiske detaljer
Main Authors: Pratt, Stephen C., Daly, Mark J., Kruglyak, Leonid
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288151/
https://ncbi.nlm.nih.gov/pubmed/10712227
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