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Variance-Components Methods for Linkage and Association Analysis of Ordinal Traits in General Pedigrees

Many complex human diseases such as alcoholism and cancer are rated on ordinal scales. Well-developed statistical methods for the genetic mapping of quantitative traits may not be appropriate for ordinal traits. We propose a class of variance-component models for the joint linkage and association an...

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Detalhes bibliográficos
Main Authors: Diao, G., Lin, D. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003595/
https://ncbi.nlm.nih.gov/pubmed/19918762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20453
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