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Variance-Components Methods for Linkage and Association Analysis of Ordinal Traits in General Pedigrees
Many complex human diseases such as alcoholism and cancer are rated on ordinal scales. Well-developed statistical methods for the genetic mapping of quantitative traits may not be appropriate for ordinal traits. We propose a class of variance-component models for the joint linkage and association an...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003595/ https://ncbi.nlm.nih.gov/pubmed/19918762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20453 |
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